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師資介紹

陳思翰 助理教授

陳思翰 助理教授      
Ssu-Han Chen

現職

助理教授

地址及連絡電話

02-8792-3100 #18820

E-mail

chenssuhan@mail.ndmutsgh.edu.tw

最高學歷

國防醫學院 醫學科學研究所 博士

經歷

2023. 08-present 國防部軍醫局少校視察
2021. 05-2023.07 國防部軍醫局少校科員
2019. 12-2021.04 國防部醫務組少校藥劑官
2014. 03-2019.11 三軍總醫院採購官、衛補官、裝審會幹事

研究領域

腦癌致病基因之篩選與分子機制、基因依賴性與藥物合併療效評估、生物資訊學探討基因體與疾病之關聯性

著作

1.Chen SH, Chiu SJ, Hu TM. Superoxide dismutase as a novel macromolecular nitric oxide carrier: preparation and characterization. Int J Mol Sci. 2012 Oct 29;13(11):13985-4001
2.Chen SH, Lin HH, Li YF, Tsai WC, Hueng DY. Clinical Significance and Systematic Expression Analysis of the Thyroid Receptor Interacting Protein 13 (TRIP13) as Human Gliomas Biomarker. Cancers (Basel). 2021 May 12;13(10):2338.
3.Lin HH, Tsai WC, Tsai CK, Chen SH, Huang LC, Hueng DY, Hung KC. Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade Gliomas. J Mol Neurosci. 2021 Aug;71(8):1614-1621.
4.Kao Y, Tsai WC, Chen SH, Hsu SY, Huang LC, Chang CJ, Huang SM, Hueng DY. Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomas. Sci Rep. 2021 Sep 17;11(1):18541.
5.Chou YL, Hsu KF, Chen SH, Lin SY, Yeh MK, Lin CK, Tsai YM. Distinct Biodistribution of Natural Killer Cell-Derived Exosomes in an Orthotopic A549 Lung Cancer Mouse Model: Implications for Potent Targeted Drug Delivery. Life (Basel). 2026 Apr 13;16(4):654.

主持計畫

1.To investigate the cytotoxicity and the molecular mechanism of NK exosomes combined with Temozolomide on temozolomideresistant glioblastoma (115年國防研究計畫,執行中)

2.Brain tumor and neuroblastoma genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis (115年國軍桃園民診計畫,執行中)
3.Integrating Transcriptomic and Dependency Profiling to Explore Vulnerabilities as Lethal Targets in PTEN-mutant Glioblastoma (116年國軍桃園民診計畫,已送審)

4.IIntegrating Transcriptomic and Dependency Profiling to Uncover Metabolic Vulnerabilities as Lethal Targets in Ewing Sarcoma (116年三總民診計畫,已送審)

其他資訊

RESEARCH · PUBLICATIONS · PROJECTS

研究・學術成果

研究主軸

腦瘤分子標記與細胞外囊泡研究
以腦癌基因與表現資料解析腫瘤脆弱性,並參與免疫細胞外泌體的遞送研究。
官網研究方向:腦癌致病基因篩選與分子機制、基因依賴性與藥物合併、生物資訊結合基因體及疾病
01TRIP13/腦瘤標記02SLC16A1/腫瘤代謝03NK細胞外泌體分布三項主軸依近年代表論文歸納,詳細研究方向請洽本人。

研究領域關鍵字雲

整理自 5 篇論文

字體大小代表該主題在論文與計畫中出現的頻率;顏色對應研究主軸。將滑鼠移到關鍵字上可看到英文名稱與統計。

腦膠質瘤標記腫瘤代謝NK 細胞外泌體癌症生物標記TRIP13SLC16A1 / MCT1免疫細胞遞送一氧化氮載體存活預測與病理分級細胞表面標記肺癌模式基因依賴性與藥物合併系統性表現分析體內分布Shugoshin 2
TRIP13/腦瘤標記SLC16A1/腫瘤代謝NK細胞外泌體分布研究方法與技術

研究論文

5 篇論文
20261 篇5.Distinct Biodistribution of Natural Killer Cell-Derived Exosomes in an Orthotopic A549 Lung Cancer Mouse Model: Implications for Potent Targeted Drug DeliveryLife (Basel) 2026;16(4):654・IF 3.420213 篇4.Clinical significance and systematic expression analysis of the thyroid receptor interacting protein 13 (Trip13) as human gliomas biomarker第一作者Cancers 13(10)・IF 4.43.Overexpression of Cell-Surface Marker SLC16A1 Shortened Survival in Human High-Grade GliomasJournal of Molecular Neuroscience 71(8):1614-1621・IF 2.72.Shugosin 2 is a biomarker for pathological grading and survival prediction in patients with gliomasScientific Reports 11(1)・IF 3.920121 篇1.Superoxide dismutase as a novel macromolecular nitric oxide carrier: Preparation and characterizationInternational Journal of Molecular Sciences 13(11):13985-14001・IF 4.9書目依 2026-09-23 彙整表,IF 為 2025 JCR;點論文題名可開啟原文(DOI)。

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  • 更新日期:2026-05-20