最高學歷
美國南加州大學顱顏分子生物學博士
學位
美國南加州大學顱顏分子生物學博士 (2018/08-2022/12)
國防醫學院生物化學研究所碩士 (2014/09-2016/07)
國防醫學院藥學系學士 (2008/09-2012/06)
教授課程
有機化學實驗 (醫、牙、藥)
生物化學實驗 (醫、牙、藥)
有機化學 (護理、公衛)
生物化學(護理、公衛)
分子生物學 (碩)
生物化學專題討論 (碩)
生物化學研究技術(碩)
獲獎情形
113年國防醫學院優良導師
研究興趣
Hox基因功能及調控機制之研究
在分子層面及表觀遺傳層面研究癌症轉移之機制
篩選真菌天然物以開發新穎傷口癒合治療劑和抗癌治療劑
研究計畫
2025
MND-MAB-D-114168 篩選真菌天然物以開發新穎傷口癒合治療劑 (1/3)
2024
MND-MAB-D-113137 研究皮膚區域專一性機制以促進傷口癒合及皮膚再生之治療策略
NSTC 113-2320-B-016-009 皮膚區域特異性和HoxC基因簇的表觀遺傳調控機制
研究論文
Hsieh Li SM, Liu ST, Chang YL, Ho CL, and Huang SM (2018). Metformin causes cancer cell death through downregulation of p53-dependent differentiated embryo chondrocyte 1, Journal of Biomedical Science, 25.1: 1-13. (IF = 11.000; Cell Biology, 27/191= 14.14%)
Kuo CL, Hsieh Li SM, Liang SY, Liu ST, Wang WM, Yen LC, and Huang SM (2019)The antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1, Cancer Management and Research, 11:6567-6579. (IF = 3.602; Oncology, 154/245= 62.86%)
Li J, Lee MO, Davis BW, Wu P, Hsieh Li SM, Chuong CM, and Andersson, L. (2021) The crest phenotype in domestic chicken is caused by a 195 bp duplication in the intron of HOXC10, G3, 11.2: jkaa048. (IF = 3.542; Genetics & Heredity, 86/175= 49.14%)
Wu, P, Jiang TX, Lei M, Chen CK, Hsieh Li SM, Widelitz RB, and Chuong CM (2021)Cyclic growth of dermal papilla and regeneration of follicular mesenchymal components during feather cycling, Development, 148.18: dev198671. (IF = 6.862; Developmental Biology, 5/39=12.82%)
Hsieh Li SM, Liu ST, Chang YL, Chen GS, and Huang SM (2022) Identification of agents that ameliorate hyperphosphatemia-suppressed myogenin expression involved in the Nrf2/p62 pathway in C2C12 skeletal muscle cells, International Journal of Molecular Sciences, 23.23: 15324. (IF = 5.6; Biochemistry & Molecular Biology, 66/285=23.16%)
Ou KL, Chen CK, Huang JX, Chang WJ, Hsieh Li SM, Jiang TX, Widelitz RB, Lansford R, and Chuong CM (2024) Adaptive patterning of vascular network during avian skin development: Mesenchymal plasticity and dermal vasculogenesis, Cells & Development, 179: 203922. (IF = 2.1; Developmental Biology, 23/39=58.97%)
Hsieh Li SM, Liang YC, Jiang TX, Jea WC, Chen CK, Lu J,Núñez-León1 D, Yu Z, Lai YC, Widelitz RB, Andersson L, Wu P, and Chuong CM (2025) Skin regional specification and higher-order HoxC regulation, Science Advances, 11(12), eado2223. (IF = 11.7; Multidisciplinary Sciences , 11/134=8.2%)