聯絡電話

(02) 8792-3100 ext. 18649

聯絡地址

台北市內湖區民權東路六段 161 號 國防醫學大學藥理所

E-MAIL

ymlee@mail.ndmutsgh.edu.tw

主要研究方向

近五年研究成果目錄

A. 期刊論文： *: 責任作者; ^#: equal contribution

1.    Yung-Chieh Tsai, Chyi-Wen Wang, Bo-Yao Wend, Po-Shiuan Hsieh, Yen-Mei Lee, Mao-Hsiung Yen, Pao-Yun Cheng*. Involvement of the p62/Nrf2/HO-1 pathway in the browning effect of irisin in 3T3-L1 adipocytes. Molecular and Cellular Endocrinology 2020;514:110915; SCI, IF: 3.6, Ranking: 34.2 % (Endocrinology & Metabolism 66/193).

2. Ni-Chun Kuo, Shieh-Yang Huang, Chien-Yi Yang, Hsin-Hsueh Shen*, and Yen-Mei Lee*. Involvement of HO-1 and autophagy in the protective effect of magnolol in hepatic steatosis-induced NLRP3 inflammasome activation in vivo and in vitro. Antioxidants 2020;9:924; SCI, IF: 6.6, Ranking: 11.1 % (Chemistry, Medicinal 8/72).

3. Je-Ming Hu, Chih-Hsueng Hsu, Yu-Chun Lin, Ching-Wen Kung, Shu-Ying Chen, Wen-Ting Lin, Pao-Yun Cheng, Hsin-Hsueh Shen*, and Yen-Mei Lee*. Ethyl pyruvate ameliorates heat stroke-induced multiple organ dysfunction and inflammatory responses by induction of stress proteins and activation of autophagy in rats. International Journal of Hyperthermia 2021;38(1):862-874; SCI, IF: 3.0, Ranking: 27.7 % (Radiology, Nuclear Medicine & Medical Imaging 59/213).

4. Pang-Yen Liu, Hsin-Hsueh Shen, Ching-Wen Kung, Shu-Ying Chen, Chia-Hsien Lu, Yen-Mei Lee*. The role of HSP70 in the protective effects of NVP-AUY922 on multiple organ dysfunction syndrome in endotoxemic rats. Frontiers in Pharmacology 2021;12:724515; SCI, IF: 4.8, Ranking: 14.5 % (Pharmacology & Pharmacy 51/352).

5. Zheng‑Zong Lai, Hsin‑Hsuen Shen, Yen‑Mei Lee*. Inhibitory effect of β‑escin on Zika virus infection through the interruption of viral binding, replication, and stability. Scientific Reports 2023;13:10014; SCI, IF: 3.9, Ranking: 18.4 % (Multidisciplinary sciences 25/136).

6. Tong Pan, Yen-Mei Lee, Eiki Takimoto, Kazutaka Ueda, Pang-Yen Liu*, Hsin-Hsueh Shen. Inhibitory effects of naringenin on estrogen deficiency-induced obesity via regulation of mitochondrial dynamics and AMPK activation associated with white adipose tissue browning. Life Sciences 2024;340:122453; SCI, IF: 5.1, Ranking: 12.5 % (Pharmacology & Pharmacy 44/352).

7. Shieh-Yang Huang^#, Ming-Ting Chung^#, Ching-Wen Kung, Shu-Ying Chen, Yi-Wen Chen, Tong Pan, Pao-Yun Cheng, Hsin-Hsueh Shen*, Yen-Mei Lee*. Alpha-lipoic acid induces adipose tissue browning through AMP-activated protein kinase (AMPK) signaling in vivo and in vitro. Journal of Obesity & Metabolic Syndrome, 2024;33:1-12; ESCI, IF: 7.9, Ranking: 8.3 % (Endocrinology & Metabolism 16/193).

8. Zheng-Zong Lai, I-Chuan Yen, Hao-Yuan Hung, Chen-Yang Hong, Chih-Wei Lai, Yen-Mei Lee*. In Vitro Antiviral Activity of Rhodiola crenulata Extract against Zika Virus and Japanese Encephalitis Virus: Viral Binding and Stability. Pharmaceuticals 2024;17: 988; SCI, IF: 4.8, Ranking: 14.5 % (Pharmacology & Pharmacy 51/352).

9. Hsiang-Yu Yang*, Kwok-Keung Lam, Chien-Ju Chou, Bo-Yao Wen, Chung-Bai Wang, Yen-Mei Lee, Chih-Yuan Lin, Pao-Yun Cheng*. Ferulic acid ethyl ester modulates electrical remodeling in cardiomyocytes exposed to TNF-α-stimulated adipocyte secretome via Nrf2/HO-1 pathway. Journal of Nutritional Biochemistry 2025;145:110005; SCI, IF: 4.9, Ranking: 15.9 % (Nutrition & Dietetics 18/113).

10. Tong Pan, Shu-Ying Chen, Ching-Wen Kung, Hsuan-Yu Chen, Pao-Yun Cheng, Hsin-Hsueh Shen, Ing-Luen Shyu*, Yen-Mei Lee*. Coenzyme Q10 ameliorates obesity by promoting white adipose tissue browning and preserving mitochondrial dynamics in ovariectomized rats fed a high-fat diet. Journal of Nutritional Biochemistry 2026;149:110187; SCI, IF: 4.9, Ranking: 15.9 % (Nutrition & Dietetics 18/113).

B. 研討會論文

1. Yen-Mei Lee, Yu-Hsuan Tseng. Methyl eugenol improves ovariectomy-induced osteoporosis in rats and suppresses osteoclastogenesis in vitro. Poster no. 105, ASCEPT, APFP & APSA Joint Congress 2024, 1-4, Dec., Melbourne, Australia.

研究領域