學位

臺北醫學大學 醫學科學研究所 博士

專長學科

1.血管新生、血管重塑之性別差異
2.內分泌生理學
3.性荷爾蒙相關癌症（如前列腺癌）

經歷

1.中央研究院生物醫學科學研究所 博士後研究員
2.三軍總醫院心臟血管外科 助理教授
3.美國哈佛大學 -波士頓兒童醫院心血管中心 短期訪問學者
4.新加坡中央醫院Singapore General Hospital 放射醫學影像實習
5.美國生理學會(APS) 會員

近年學術論文著作

1.Huo YN, Yang HY, Ke HY, Lin CY, Tsai CS. (2024, Nov). Androgen receptor activation inhibits endothelial cell migration in vitro and angiogenesis in vivo . Eur J Cell Biol, 103(4):151456.

2.Liu CH, Wen ZH, Huo YN, Lin CY, Yang HY, Tsai CS. (2024, Aug). Piscidin-1 regulates lipopolysaccharide-induced intracellular calcium, sodium dysregulation, and oxidative stress in atrial cardiomyocytes.. Eur J Pharmacol., 5;976:176695.

3.Lu MK, Huo YN, Tai BY, Lin CY, Yang HY, Tsai CS. (2024, Jul). Ziprasidone triggers inflammasome signaling via PI3K-Akt-mTOR pathway to promote atrial fibrillation.. Biomed Pharmacother, 75:116649.

4.H. C. Wang, Y. N. Huo and W. S. Lee (2023, Nov). Activation of progesterone receptor is essential for folic acid-regulated cancer cell proliferation and migration . JOURNAL OF NUTRITIONAL BIOCHEMISTRY.

5.H. Y. Yang, J. Y. Chen, Y. N. Huo, P. L. Yu, P. Z. Lin, S. C. Hsu, et al. (2022, May). The Role of Sirtuin 1 in Palmitic Acid-Induced Endoplasmic Reticulum Stress in Cardiac Myoblasts . LIFE SCIENCES.

6.H. C. Wang, Y. N. Huo and W. S. Lee (2020, Nov). Folic acid prevents the progesterone-promoted proliferation and migration in breast cancer cell lines . EUROPEAN JOURNAL OF NUTRITION.

7.X. S. Cheng, Y. N. Huo, Y. Y. Fan, C. X. Xiao, X. M. Ouyang, L. Y. Liang, et al. (2020, Aug). Mindin serves as a tumour suppressor gene during colon cancer progression through MAPK/ERK signalling pathway in mice . Cellular and Molecular Medicine.

8.Y. N. Huo, S. D. Yeh and W. S. Lee (2019, Nov). Androgen receptor activation reduces the endothelial cell proliferation through activating the cSrc/AKT/p38/ERK/NFκB-mediated pathway. J Steroid Biochem Mol Biol.

9.P. C. Ting, W. R. Lee, Y. N. Huo, S. P. Hsu and W. S. Lee (2019, Jan). Folic acid inhibits colorectal cancer cell migration. JOURNAL OF NUTRITIONAL BIOCHEMISTRY.

10.H. C. Wen, Y. N. Huo, C. M. Chou and W. S. Lee (2018, Nov). PMA inhibits endothelial cell migration through activating the PKC-delta/Syk/NF-kappaB-mediated up-regulation of Thy-1 . Scientific Reports.

11.Y. N. Huo, W. Chen and X. X. Zheng (2015, Nov). ROS, MAPK/ERK and PKC play distinct roles in EGF-stimulated human corneal cell proliferation and migration. Cell Mol Biol.

12. T. S. Lee, J. J. Lin, Y. N. Huo and W. S. Lee (2015, Jul). Progesterone Inhibits Endothelial Cell Migration Through Suppression of the Rho Activity Mediated by cSrc Activation . J Cell Biochem.

13.Sung-Po Hsu 1, Ho-Ching Yang, Chun-Ting Kuo, Heng-Ching Wen, Li-Ching Chen, Yen-Nien Huo, Wen-Sen Lee (2015, Jan). Progesterone receptor-NFkappaB complex formation is required for progesterone-induced NFkappaB nuclear translocation and binding onto the p53 promoter . Endocrinology.

14.H. C. Wen, C. Kao, R. C. Hsu, Y. N. Huo, P. C. Ting, L. C. Chen (2013, Apr). Thy-1-induced migration inhibition in vascular endothelial cells through reducing the RhoA activity. PLoS One.