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Po-Shiuan Hsieh

🏫 Graduate Institute of Physiology
Professor Po-Shiuan Hsieh
Po-Shiuan Hsieh Professor
📧 Contact
📚 Publication
  1. Pei-Chi Chan, Chun-Han Jhuang, Hsin-Yi Chang, Po Shiuan Hsieh* (2026, Mar). Brown Adipocyte-Derived Serum Amyloid A 3 Alters Diet-Induced Thermogenesis and Impacts Weight Gain. Journal of Nutrional Biochemistry, 151, 2026, 110263. (SCI, Q1, 18/112, Nutrition & Dietetics). NSTC 111-2320-B-016-016-MY3. Corresponding author.
  2. Pei-Chi Chan, Pei-Ru Lin, Yu-Feng Tian, Po-Shiuan Hsieh* (2026). Cold-Induced Serum Amyloid A3 Amplifies cAMP–PKA Signaling to Drive Adaptive Thermogenesis in Brown Adipocytes. iScience. (Accepted). (SCI, Q1, 19/134, Multidisciplinary Sciences). NSTC 111-2320-B-016-003-MY3. Corresponding author.
  3. Tai C-S, Chung H-Y, Lin T-H, Chang C-K, Perng C-L, Po-Shiuan Hsieh*, Shang H-S, Jian M-J. (2025, Oct). Rapid Nanopore Sequencing of Positive Blood Cultures Using Automated Benzyl-Alcohol Extraction Improves Time-Critical Sepsis Management. Antibiotics, 14(10):1001. (SCI, 17/137, Q1, Infectious Diseases). Corresponding author.
  4. Jiung-Pang Huang, Kuan-Hsing Chen, Po-Shiuan Hsieh, Chao-Yu Kuo, Chao Lan Yu & Li-Man Hung (2025, Sep). Genetic deficiency of CCL5 exhibits the phenotypes of HFpEF and aggravates apoptotic cardiomyopathy in HFD-induced diabetic mice. Journal of Molecular Medicine. (SCI, Q1, Medicine, Research & Experimental).
  5. Tai C, Jian M, Lin T, Chung H, Chang C, Perng C, Po-Shiuan Hsieh*, Shang H. (2025, Jul). Analytical performance evaluation of a multiplex real-time RT-PCR kit for simultaneous detection of SARS-CoV-2, influenza A/B, and RSV. Peer Journal, 13:e19693. (SCI, 47/135, Q2, Multidisciplinary Sciences). Corresponding author.
  6. Chuang-Yen Huang, I-Shan Han, Po-Shiuan Hsieh, Min-Chien Tsai, Hung-Che Chien (2025, Jan). Dichloroacetate, a pyruvate dehydrogenase activator, alleviates high-fat-induced impairment of myogenic differentiation in skeletal muscles. Basic & Clinical Pharmacology & Toxicology. (SCI, 167/329, Pharmacology & Pharmacy).
  7. Chuang-Yen Huang, I-Shan Han, Po-Shiuan Hsieh, Min-Chien Tsai, Hung-Che Chien (2024, Nov). Dichloroacetate, a pyruvate dehydrogenase activator, alleviates high-fat-induced impairment of myogenic differentiation in skeletal muscles. Basic & Clinical Pharmacology & Toxicology, 2024; 1–12. doi:10.1111/bcpt.14102. (SCI, 167/329, Pharmacology & Pharmacy).
  8. Tai, C.-S.; Jian, M.-J.; Lin, T.-H.; Chung, H.-Y.; Chang, C.-K.; Perng, C.-L.; Hsieh, P.-S.; Shang, H.-S. (2024, Oct). Diagnostic Accuracy of the LabTurbo QuadAIO Common Flu Assay for Detecting Influenza A Virus, Influenza B Virus, RSV, and SARS-CoV-2. Diagnostics, 2024, 14, 2200. (SCI, 59/329, Medicine, general & internal). Corresponding author.
  9. Jung-Mou Yang, I-Shan Han, Tsung-Hua Chen, Po-Shiuan Hsieh, Min-Chien Tsai, Hung-Che Chien (2024, Sep). Pharmacological activation of pyruvate dehydrogenase by dichloroacetate protects against obesity-induced muscle atrophy in vitro and in vivo. European Journal of Pharmacology, 979, 176854. (SCI, 75/254, Pharmacology & Pharmacy).
  10. Sy-Jou Chen, Hung-Che Chien, Shih-Hung Tsai, Yu-Sin Jheng, Yi Chen, Po-Shiuan Hsieh, Pi-Fen Tsui, Shu Chien, Min-Chien Tsai (2024, Jul). Melatonin Ameliorates Atherosclerotic Plaque Vulnerability by Regulating PPARδ-Associated Smooth Muscle Cell Phenotypic Switching. Journal of Pineal Research, 76:e12988. https://doi.org/10.1111/jpi.12988. (SCI, 13/186, Endocrine & Metabolism).
  11. Chien-Wei Chen, Luen-Kui Chen, Yi-Ting Chung, Shui-Yu Liu, Shuoh-Wen Chen, Yuan-I Chang, Po-Shiuan Hsieh, Chi-Chang Juan (2023, Dec). Cysteinecysteine Chemokine Receptor Type 5 Plays a Critical Role in Exercise Performance by Regulating Mitochondrial Content in Skeletal Muscle. Inflammation, 46(6), 2089–2101. (SCI, 63/200, Medicine - Immunology and Allergy).
  12. Chih‐Feng Lien, Chin‐Sheng Lin, Song‐Kun Shyue, Po-Shiuan Hsieh, Sy‐Jou Chen, Yi‐Tan Lin, Shu Chien, Min‐Chien Tsai (2023, Mar). Peroxisome proliferator‐activated receptor δ improves the features of atherosclerotic plaque vulnerability by regulating smooth muscle cell phenotypic switching. British Journal of Pharmacology, 1–17. https://doi.org/10.1111/bph.16074. (SCI, 14/303, Q1, Pharmocology & Pharmacy). MOST 109-2314-B-016-042-MY3.
  13. Nian-Sheng Tzeng, Yu-Yin Yang, Chen-Cheng Lin, Po-Shiuan Hsieh, Yia-Ping Liu (2023, Jan). Effects of Early Risperidone Treatment on Metabolic Parameters in Socially Isolated Rats—Implication of Antipsychotic Intervention across Developmental Stages of Schizophrenia. Journal of Integrative Neuroscience, 22(1), 22. (SCI, 81/110, Neuroscience, general Neuroscience).
  14. Chan, Pei-Chi, Chieh-Hua Lu, Hung-Che Chien, Yu-Feng Tian, and Po-Shiuan Hsieh. (2022, Nov). Adipose Tissue-Derived CCL5 Enhances Local ProInflammatory Monocytic MDSCs Accumulation and Inflammation via CCR5 Receptor in High-Fat Diet-Fed Mice. International Journal of Molecular Sciences, 23(22):14226. (SCI, 69/297, Q1, Biochemistry & Molecular Biology). NSTC 111-2320-B-016-003-MY3. Corresponding author.
  15. Liao, Tzu-Chieh, Jiung-Pang Huang, Yu-Ting Tsai, Wei-Ching Shih, Chi-Chang Juan, Po-Shiuan Hsieh, Li-Man Hung, Chao-Lan Yu (2022, Oct). Granulocytic MDSC with Deficient CCR5 Alleviates Lipogenesis and Inflammation in Nonalcoholic Fatty Liver Disease. International Journal of Molecular Sciences, 23(21):13048. (SCI, 69/297, Q1, Biochemistry & Molecular Biology).
  16. Yeh, Chia-Tsui, Chia-Ying Lee, Yi-Jung Ho, Sin-An Chen, Liang-Yu Chen, Ping-Cheng Liu, Yuan-Fan Chin, An-Yu Chen, Po-Shiuan Hsieh, Yi-Jen Hung, Cheng-Cheung Chen, Yu-Chie Wang, and Guan-Chiun Lee (2022, Sep). Immunoglobulin Y Specific for SARS-CoV-2 Spike Protein Subunits Effectively Neutralizes SARS-CoV-2 Infectivity and Ameliorates Disease Manifestations In Vivo. Biomedicines, 10(11):2774. https://doi.org/10.3390/biomedicines10112774. (SCI, 121/297, Biochemistry & Molecular Biology).
  17. Chan, Pei-Chi, and Po-Shiuan Hsieh. (2022, Aug). The Role and Regulatory Mechanism of Brown Adipose Tissue Activation in Diet-Induced Thermogenesis in Health and Diseases. International Journal of Molecular Sciences, 23(16):9448. (SCI, 69/297, Q1, Biochemistry & Molecular Biology). MOST 110-2320-B-016-003. Corresponding author.
  18. Li-Jen Tsai, Chi-Hsiang Chung, Chien-Jung Lin, Sheng-Chiang Su, Feng-Chih Kuo, Jhih-Syuan Liu, Kuan-Chan Chen, Li-Ju Ho, Chih-Chun Kuo, Chun-Yung Chang, Ming-Hsun Lin, Nain-Feng Chu, Chien-Hsing Lee, Chang-Hsun Hsieh, Yi-Jen Hung, Po-Shiuan Hsieh, Fu-Huang Lin, Chieh-Hua Lu, Wu-Chien Chien (2022, Jun). Traditional Chinese medicine attenuates hospitalization and mortality risks in diabetic patients with carcinoma in situ in Taiwan. Integrative Medicine Research, 11(2):100831. (SCI, 7/30, Q1, Integrative & Complementary Medicine).
  19. Po-Chang Shih, Yi-Wen Mao, Yi-Wen Mao, Yi-Wen Mao, Jhe-Wei Hu, Han-Yi Hsieh, Tsai-Miao Shih, Lu-Ping Lu, Wei-Hua Chang, Chan-Hui Huang, ChiaHung Lin, Chih-Hung Lin, Peng Tan, Ya-Ching Yang, Ming-Hong Chien, ChenChe Su, Cheng-Hsin Yeh, Pei-Yun Chuang, Tien-Lan Hsieh, Ching-Cheng Wang, Po-Shiuan Hsieh, Teh-Ying Chou, and Guochuan Emil Tsai* (2022, May). Development of Ultrapure and Potent Tannic Acids as a Pan-coronal Antiviral Therapeutic. ACS Pharmacology and Translational Sciences, 2022, 5(6), 400–412. (SCI, 101/357, Pharmacology & Pharmacy).
  20. Pei-Chi Chan, Li-Man Hung, Jiung-Pang Huang, Yuan-Ji Day, Chao-Lan Yu, Feng-Chih Kuo, Chieh-Hua Lu, Yu-Feng Tian, Po-Shiuan Hsieh (2022, Jan). Augmented CCL5/CCR5 signaling in brown adipose tissue inhibits adaptive thermogenesis and worsens insulin resistance in obesity. Clinical Science, 136(1):121–137. (SCI, 31/140, Medicine, Research & Experimental). MOST 107-2320-B-016-MY3. Corresponding author.
  21. Pei-Chi Chan, Po-Shiuan Hsieh (2021, Dec). The chemokine systems at the crossroads of inflammation and energy metabolism in the development of obesity. International Journal of Molecular Science, 22(24):13528. (SCI, 67/295, Biochemistry & Molecular Biology). MOST 107-2320-B-016-MY3. Corresponding author. https://doi.org/10.3390/ijms222413528.
  22. Pei-Chi Chan, Min-Tser Liao, Chieh-Hua Lu, Yu-Feng Tian, Po-Shiuan Hsieh (2021, Jan). Targeting inhibition of CCR5 on improving obesity-associated insulin resistance and impairment of pancreatic insulin secretion in high fat-fed rodent models. European Journal of Pharmacology, 891, 173703. (SCI, 96/271 Pharmacology & Pharmacy). MOST 107-2320-B-016-010-MY3. Corresponding author.
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  • 更新日期:2026-07-13