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::: Shu-Yi Lin

🧪 PHARMACEUTICAL SCIENCE
林書儀 助理教授
Shu-Yi Lin
Assistant Professor
LABORATORY INTRUDUCTION
In recent years, rapid advancements in fields such as gene sequencing, bioinformatics, and synthetic biology have enabled a deeper understanding of natural products at the genetic and protein levels. Currently, our research primarily utilizes genome mining and heterologous expression in fungi to explore natural products produced by fungal biosynthetic gene clusters and their biosynthetic pathways. We also conduct screening for relevant pharmacological activities. Additionally, we focus on the discovery of bioactive natural products guided by bioactivity assays.
📞 Contact Information
Office : R9329 / Lab : R9328
Tel: +886-2-8792-3100 ext.18892 / Lab: 18891
E-mail： shuyilin@mail.ndmctsgh.edu.tw
🎓 Education
Ph. D., Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Dec. 2023
M. S., Graduate Institute of Pharmacy, National Defense Medical Center, Jun. 2016
B. S., School of Pharmacy, National Defense Medical Center, Jun. 2012

🏛 Experience
2024/05–present Assistant professor, School of Pharmacy, National Defense Medical Center
2018/08–2024/04 Lecturer, School of Pharmacy, National Defense Medical Center
2016/08–2018/08 Adjunct lecturer, School of Pharmacy, National Defense Medical Center
2018/01–2018/08 Pharmacist, Hualien Armed Forces General Hospital
2012/07–2017/12 Military service, Armed Forces Medical Supplies Office
🔬 Research Interest
Synthetic biology, Natural product chemistry
🧾 Publications
(Star-sign*: correspondent)
  1. Shu-Yi Lin, C. Elizabeth Oakley, Cory B. Jenkinson, Yi-Ming Chiang, Ching-Kuo Lee, Christopher G. Jones, Paul M. Seidler, Hosea M. Nelson, Richard B. Todd, Clay C. C. Wang*, and Berl R. Oakley*. A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters: discovery of the Aspergillus fumigatus sartorypyrone biosynthetic pathway. Chemical Science. 2023;14(40):10983–11284. (IF=8.4)
  2. Chris Rabot, Yuhao Chen, Shu-Yi Lin, Ben Miller, Yi-Ming Chiang, C. Elizabeth Oakley, Berl R. Oakley, Clay C. C. Wang*, and Travis J. Williams*. Polystyrene upcycling into fungal natural products and a biocontrol agent. Journal of the American Chemical Society. 2023;145(9):5222-5230. (IF=15.0)
  3. Shu-Yi Lin, Meng-Ren Wang, Shih-Jiuan Chiu, Chien-Yu Lin, and Teh-Min Hu*. S-Nitrosothiols (SNO) as light-responsive molecular activators for post-synthesis fluorescence augmentation in fluorophore-loaded nanospheres. Journal of Materials Chemistry B. 2018;6(1):153–164. (IF=7.0)
🧾 Patent
  1. Swati Bijlani, Chris Rabot, Yuhao Chen, Shu-Yi Lin, Ben Miller, Yi-Ming Chiang, Clay C. C. Wang, and Travis J. Williams. Conversion of Waste Plastics to High-Value Metabolites. 2022, USC-0336PUSP.
  2. Chris Rabot, Yuhao Chen, Shu-Yi Lin, Ben Miller, Yi-Ming Chiang, Clay C. C. Wang, and Travis J. Williams. Polystyrene upcycling into fungal natural products and a biocontrol agent. 2023, USC-0343PRV.
🧾 Conference Papers
  1. Shu-Yi Lin, C. Elizabeth Oakley, Cory B. Jenkinson, Yi-Ming Chiang, Ching-Kuo Lee, Christopher G. Jones, Paul M. Seidler, Hosea M. Nelson, Richard B. Todd, Clay C. C. Wang, and Berl R. Oakley. A heterologous expression platform in Aspergillus nidulans for the elucidation of cryptic secondary metabolism biosynthetic gene clusters in Aspergillus fumigatus. AAPS Moving Targets Conference, Los Angeles, USA, Aug. 2023. (Winner of the 2023 Young Investigator Award)
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  • Update Date:2026-03-25
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