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林宏糧 教授

🧪 藥物科學領域
林宏糧 教授
林宏糧 教授
Hong-Liang Lin
實驗室簡介
本研究室為製劑設計學實驗室，主要研究領域為藥物製劑開發與藥品傳輸系統研究，結合藥劑學、工業藥學、製藥工業、化工材料、生醫科學等評估方法，建立藥品從處方設計、製程優化到品質評估的完整量產製劑研究平台。實驗室亦以開發提升藥物穩定性、生體可用率、控制釋放特性及臨床應用價值為核心目標，發展具創新性與實用性的藥品製劑技術並具量產基利。除此之外，實驗室也重視藥劑相關理論與學生紮實的工業藥學基礎實務經驗操作能力，並強調跨域思考、解決問題分析能力與跨領域整合能力，以因應未來現代AI製藥產業與學術研究發展需求，重塑學術倫理、團隊合作研究精神。
📞 聯絡資訊
辦公室房間號碼：R9327｜實驗室：R9326
電話：02-87923100 ext.18890
E-mail：hlglin@mail.ndmutsgh.edu.tw

🎓 學歷
1993 ~ 1998 台北醫學院 藥學系 藥學士
1998 ~ 2000 台北醫學院 藥學研究所（藥劑學組）藥學碩士
2000 ~ 2008 台北醫學大學 藥學系（藥劑學組）藥學博士
🏛 現職
2026/02 ~ Present 國防醫學大學 藥學系 教授
2019      ~ Present 經濟部／食藥署 採購案招標案遴選委員／計畫審查委員
2018      ~ Present 高雄市政府原住民委員會 採購案招標案遴選委員／部落大學課程審查委員／諮詢委員
2025/12 ~ 2027/12 屏東縣政府文化資產保護所 安全及防護委員會委員
2025/12 ~ 2028/12 嘉義縣政府衛生局 安衛委員會委員
2016/09 ~ Present 台灣藥學會 工業藥學委員
🏛 經歷
2008/08 ~ 2009/06 台北醫學大學 藥學系 博士後研究員
2009/07 ~ 2010/02 財團法人國家衛生研究院（生物技術與藥物研究組）博士後研究員
2010/02 ~ 2010/07 元培科技大學 生物技術系 兼任助理教授
2010/03 ~ 2010/07 財團法人醫藥品查驗中心 基礎醫學組研究員／審查員（化學製造與管制）
2010/08 ~ 2014/07 元培科技大學 生物技術系 專任助理教授
2011/08 ~ 2013/07 元培科技大學 研發處產學合作組 組長
2012/08 ~ 2013/07 元培醫事科技大學 研發處企劃組 組長
2014/08 ~ 2015/01 元培醫事科技大學 生物科技暨製藥技術系 專任助理教授
2014/08 ~ 2017/07 元培醫事科技大學 研發處產學合作中心 主任
2015/02 ~ 2017/07 元培醫事科技大學 生物科技暨製藥技術系 副教授
2016/08 ~ 2017/07 新北市生技醫療聯盟 分團顧問
2019/02 ~ 2021/01 高雄醫學大學 藥學系 助理教授
2021/02 ~ 2024/07 高雄醫學大學 藥學系 副教授
2024/08 ~ 2026/01 高雄醫學大學 藥學系 教授
2025/01 ~ 2026/01 高雄醫學大學 原民健康照護及文化永續研究中心 副主任
🔬 學術專長/研究領域
藥劑學、工業藥學、製藥工程、藥物傳遞系統與劑型設計、藥品製程量產放大適宜化
🛠️ 技術專長
藥物劑型設計、生技醫藥妝品量產製程適宜化、膜衣包覆技術、藥物生體相等性(BE)、試驗執行規劃設計、學名藥開發、固體劑型緩控調釋緩釋技術、藥品處方安定性改善
🧾 論文著作
※ 共計38篇，可上下捲動瀏覽
  1. Chien-Ju Lin, Bang-Yu Wen, Yu-Kai Liang, Wen-Chen You, Hsiu-O Ho, Ming-Thau Sheu, Hong-Liang Lin*, Ling-Chun Chen*. (2026) Melatonin-Loaded Sacchachitin Nanofiber Hydrogel as a Novel Non-Steroidal Platform for Atopic Dermatitis Therapy. International Journal of Nanomedicine, 21, 574853.
  2. Pu-Sheng Wei, Po-Yu Chou, Hao-Yi Hsu, Michael Chen, Yi-Jou Chen, Tung-Han Tsai, Bang-Yu Wen, Ming-Thau Sheu, Kuo-Hsiang Chuang, Hong-Liang Lin*. (2025) Nonshrinkable Thermosensitive Hydrogels Combined with Bispecific Anti-PSMA/CD3 T-Cell Engager for Effective Against Tumors in Mice Model. Int J Nanomedicine. 2025, 20, 3083–3111.
  3. Chia-Wei Chu, Wei-Jie Cheng, Bang-Yu Wen, Yu-Kai Liang, Ming-Thau Sheu, Ling-Chun Chen, Hong-Liang Lin*. (2024) Preparation and Rheological Evaluation of Thiol–Maleimide/Thiol–Thiol Double Self-Crosslinking Hyaluronic Acid-Based Hydrogels as Dermal Fillers for Aesthetic Medicine. Gels, 10(12), 776.
  4. Ling-Chun Chen, Shyr-Yi Lin, Wei-Jie Cheng, Ming-Thau Sheu, Chi-Yun Chung, Chen-Hsuan Hsu, Hong-Liang Lin*. (2023) Poloxamer sols endowed with in-situ gelability and mucoadhesion by adding hypromellose and hyaluronan for prolonging corneal retention and drug delivery. Drug Delivery, 2023, 30(1), 2158964.
  5. Chien-Ju Lin, Wen-Ting Cheng, Ling-Chun Chen, Tzu-Ling Chen, Ming-Thau Sheu, Hong-Liang Lin*. (2023) Oral metronomic therapy of pancreatic cancer with gemcitabine and paclitaxel co-loaded in lecithin-based Self-Nanoemulsifying preconcentrate (LBSNEP). International Journal of Pharmaceutics, 2023, 645(15).
  6. Chien-Ju Lin†, Hong-Liang Lin,†, Wen-Chen You, Hsiu-O Ho, Ming-Thau Sheu , Ling-Chun Chen* and Wei-Jie Cheng*. (2023) Composite Hydrogels of Ultrasound-Assisted-Digested Formic Acid-Decellularized Extracellular Matrix and Sacchachitin Nanofibers Incorporated with Platelet-Rich lasma for Diabetic Wound Treatment. Journal of Functional Biomaterials, 14(8), 423.
  7. Yu-Kai Liang, Wen-Ting Cheng, Ling-Chun Chen, Ming-Thau Sheu, Hong-Liang Lin*. (2023) Development of Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) of Ciprofloxacin Hydrochloride with Hydrophobically Modified Hydroxypropyl Methylcellulose: Formulation, Physicochemical Characterization, and In vivo Pharmacokinetics. Pharmaceutics, 15(5), 1428.
  8. Yu-Hsuan Liu, Ling-Chun Chen, Wen-Ting Cheng, Pu-Sheng Wei, Chien-Ming Hsieh, Ming-Thau Sheu, Shyr-Yi Lin, Hsiu-O Ho* and Hong-Liang Lin*. (2023) Synergistic Combination of Irinotecan and Rapamycin Orally Delivered by Nanoemulsion for Enhancing Therapeutic Efficacy of Pancreatic Cancer. Pharmaceutics. 2023 Jan 31;15(2):473.
  9. Chia-Wei Chu, Zhu Liduzi Jiesisibieke, Yu-Pei Yang, Pao-Chu Wu, Hong-Liang Lin, Tao-Hsin Tung. (2022) Association of COVID-19 vaccination with herpes zoster: a systematic review and meta-analysis. Expert Rev Vaccines. 21(5):601-608.
  10. Ling-Chun Chen, Shyr-Yi Lin, Wei-Jie Cheng, Ming-Thau Sheu, Chi-Yun Chung, Chen-Hsuan Hsu and Hong-Liang Lin. (2021) Poloxamer sols endowed with in-situ gelability and mucoadhesion by adding hypromellose and hyaluronan for prolonging corneal retention and drug delivery. Drug Deliv.
  11. Chen Ling-Chun, Cheng Wei-Jie, Lin Shyr-Yi, Hung Ming-Tse, Sheu Ming-Thau, Lin Hong-Liang, Hsieh Chien-Ming. (2021) CPT11 with P-glycoprotein/CYP 3A4 dual-function inhibitor by self-nanoemulsifying nanoemulsion combined with gastroretentive technology to enhance the oral bioavailability and therapeutic efficacy against pancreatic adenocarcinomas. Drug Deliv. 28(1):2205-2217.
  12. Chen Ling-Chun, Lin Shyr-Yi, Sheu Ming-Thau, Su Ching-Hua, Lin Hong-Liang, Hsieh Chien-Ming. (2021) Fabrication and characterization of Rhizochitosan and its incorporation with platelet concentrates to promote wound healing. Carbohydr Polym. 268:118239.
  13. Wu Meng-Huang, Wang Weu, Chao Fang-Ching, Hsieh Chien-Ming, Chen Ling-Chun, Lin Hong-Liang, Ho Hsiu-O, Huang Tsung-Jen, Sheu Ming-Thau. (2021) One-pot fabrication of sacchachitin for production of TEMPO-oxidized sacchachitin nanofibers (TOSCNFs) utilized as scaffolds to enhance bone regeneration. Carbohydr Polym. 254: 117270.
  14. Lin Hong-Liang, Cheng WT, Chen LC, Ho HO, Lin SY, Hsieh CM. (2021) Honokiol/Magnolol-Loaded Self-Assembling Lecithin-Based Mixed Polymeric Micelles (lbMPMs) for Improving Solubility to Enhance Oral Bioavailability. Int J Nanomedicine. 16:651-665. [SCI] (IF2020=6.400；R/C=56/352，PHARMACOLOGY & PHARMACY)
  15. Lin Hong-Liang, Wu Ting-Huan, Ho Hsiu-O, Chao Fang-Ching, Wu Meng-Huang, Liu Der-Zen, Chen Ling-Chun, Sheu Ming-Thau*.(2020) TEMPO-Oxidized Sacchachitin Nanofibers (TOSCNFs) Combined with Platelet-Rich Plasma (PRP) for Management of Dry Eye Syndrome. Int. J. Nanomed. 13: 7079-7094. [SCI] (IF2020=6.400；R/C=56/352，PHARMACOLOGY & PHARMACY)
  16. Lin Hong-Liang, Chen Ling-Chun, Cheng Wen-Ting, Cheng Wei-Jie, Ho Hsiu-O, Sheu Ming-Thau*.(2020) Preparation and Characterization of a Novel Swellable and Floating Gastroretentive Drug Delivery System (sfGRDDS) for Enhanced Oral Bioavailability of Nilotinib. Pharmaceutics. 12(2): 137-151. [SCI] (IF2020=6.321；R/C=31/352，PHARMACOLOGY & PHARMACY)
  17. Chao Fang-Ching, Wu Meng-Huang, Chen Ling-Chun, Lin Hong-Liang, Liu Der-Zen, Ho Hsiu-O*, Sheu Ming-Thau *.(2020) Preparation and Characterization of Chemically TEMPO-oxidized and Mechanically Disintegrated Sacchachitin Nanofibers (SCNF) for Enhanced Diabetic Wound Healing. Carbohydr. Polym. 2020(15):1721-1730. [SCI] (IF2020=9.381；R/C=1/58，CHEMISTRY, ORGANIC)
  18. Cheng Wei-Jie, Chen Ling-Chun, Ho Hsiu-O, Lin Hong-Liang, Sheu Ming-Thau *. (2018) Stearyl Polyethylenimine (stPEI) Complexed with Plasmids as the Core of Human Serum Albumin (Plasmid/stPEI/HSA) Nanoparticles Non-Covalently Bound to CRISPR/Cas9 Plasmids or siRNA for Disrupting or Silencing PD-L1 Expression for Immunotherapy. Int. J. Nanomed. 13: 7079-7094. [SCI] (IF2020=6.400；R/C=56/352，PHARMACOLOGY & PHARMACY)
  19. Lin Hong-Liang, Huang Yu-Ting, Lin Shan-Yang Lin*. (2016) Spectroscopic and thermal approaches to investigate the formation mechanism of piroxicam–saccharin co-crystal induced by liquid-assisted grinding or thermal stress. J. Therm. Anal. Calorim. 123:2345-2356. [SCI] (IF2020=4.626；R/C=18/71，THERMODYNAMICS)
  20. Lin Shan-Yang, Lin Hong-Liang, Chi Ying-Ting, Hung Ru-Ying, Huang Yu-Ting, Hsieh Wei-Hsien Hsieh, Kao Chi-Yu. (2016) Influence of Soluplus on Solid-State Properties and Physical Stability of Indomethacin-Saccharin Co-crystal Formation Prepared by Air-Drying Process. J. Pharm. Innov. 11:109-119. [SCI] (IF2020=2.750；R/C=231/352，PHARMACOLOGY & PHARMACY)
  21. Lin Shan-Yang*, Lin Hong-Liang, Chi Ying-Ting, Hung Ru-Ying, Huang Yu-Ting, Kao Chi-Yu, Hsieh Wei-Hsien. (2016) Povacoat affecting solid-state polymorphic changes of indomethacin after co-evaporation from different types of solvents via conventional and microwave drying techniques. Asian Journal of Pharmaceutical Sciences. 11(3): 376-384.[SCI] (IF2020=6.598；R/C=34/352，PHARMACOLOGY & PHARMACY)
  22. Lin Shan-Yang*, Lin Hong-Liang, Hung Ru-Ying, Huang Yu-Ting and Kao Chi-Yu. (2015) Effect of Povacoat or Soluplus on Solid-State Characterization of Indomethacin-Nicotinamide Co-Crystal Formation. Pharm. Anal. Acta. 6:8
  23. Lin Shan-Yang*, Lin Hong-Liang, Chi Ying-Ting, Huang Yu-Ting, Kao Chi-Yu, Hsieh Wei-Hsien. (2015) Thermoanalytical and Fourier transform infrared spectral curve-fitting techniques used to investigate the amorphous indomethacin formation and its physical stability in Indomethacin-Soluplus® solid dispersions. Int. J. Pharmaceut. 496: 457-465. →Int. J. Pharm.[SCI] (IF2020=5.875；R/C=18/352，PHARMACOLOGY & PHARMACY)
  24. Lin Hong-Liang, Chi Ying-Ting, Huang Yu-Ting, Kao Chi-Yu and Lin Shan-Yang*.(2015) DSC-FTIR Combined Approaches Used to Simultaneously Prepare/Determine the Amorphous Solid Dispersions of Indomethacin/Soluplus in Real-time. EC Pharmaceutical Science 2.1: 183-193.
  25. Kao Chi-Yu, Huang Huai-Han, Huang Yu-Ting, Lin Hong-Liang, Lin Shan-Yang*. (2015) Thermoanalytical and spectroscopic studies on amorphization and phase transition of amorphous indomethacin prepared by two melt-cooling processes. Sci. Letter. J. , 4: 148
  26. Lin Hong-Liang*, Zhang Gang-Chun, Lin Shan-Yang**. (2015) Real-time co-crystal screening and formation between indomethacin and saccharin via DSC analytical technique or DSC–FTIR microspectroscopy. J. Therm. Anal. Calorim. 120: 679-687. [SCI] (IF2020=4.626；R/C=18/71，THERMODYNAMICS)
  27. Lin Hong-Liang*, Zhang Gang-Chun, Huang Yu-Ting, Lin Shan-Yang**. (2014) An Investigation of Indomethacin–Nicotinamide Cocrystal Formation Induced by Thermal Stress in the Solid or Liquid State. J. Pharm. Sci. 103: 2386-2395. [SCI] (IF2020=3.534；R/C=51/216，CHEMISTRY, MULTIDISCIPLINARY)
  28. Lin Hong-Liang*, Wu Tieh-Kang, Lin Shan-Yang**. (2014) Screening and characterization of cocrystal formation of metaxalone with short-chain dicarboxylic acids induced by solvent-assistedgrinding approach. Thermochim. Acta 575: 313-321. [SCI] (IF2020=3.115；R/C=26/71，THERMODYNAMICS)
  29. Lee Lin-Wen, Hung Sheng-Feng, Lin Hong-Liang, Ho Hsiu-O, Sheu Ming-Thau*. (2013) Development of Timely Controlled-Release Systems for Chronotherapy of Propranolol with Minimization of the pH Effect in the Simulated Gastrointestinal Medium. J. Food Drug Anal. 21: 115-125. [SCI] (IF2020=6.079；R/C=29/352，PHARMACOLOGY & PHARMACY)
  30. Lin Hong-Liang, Hsu Po-Chun, Lin Shan-Yang*. (2013) Theophylline-citric acid co-crystals easily induced by DSC-FTIR microspectroscopy or different storage conditions. Asian Journal of Pharmaceutical Sciences. 8: 19-27. [SCI] (IF2020=6.598；R/C=34/352，PHARMACOLOGY & PHARMACY)
  31. Lin Hong-Liang, Zhang Gang-Chun, Hsu Po-Chun, Lin Shan-Yang*. (2013) A portable fiber-optic Raman analyzer for fast real-time screening and identifying cocrystal formation of drug-coformer via grinding process. Microchem. J. 110: 15-20. [SCI] (IF2020=4.821；R/C=12/93，CHEMISTRY, ANALYTICAL)
  32. Hsu Po-Chun, Lin Hong-Liang, Wang Shun-Li**, Lin Shan-Yang*. (2012) Solid-state thermal behavior and stability studies of theophylline-citric acid cocrystals prepared by neat cogrinding or thermal treatment. J. Solid State Chem. 192: 238-245. [SCI] (IF2020=3.498；R/C=13/43，CHEMISTRY, INORGANIC & NUCLEAR)
  33. Zhang Gang-Chun, Lin Hong-Liang*, Lin Shan-Yang**. (2012) Thermal analysis and FTIR spectral curve-fitting investigation of formation mechanism and stability of indomethacin-saccharin cocrystals via solid-state grinding process. J. Pharmaceut. Biomed. Anal. 66: 162-169. [SCI] (IF2020=3.935；R/C=16/93，CHEMISTRY, ANALYTICAL)
  34. Lin Hong-liang, Lin Shan-Yang*, Lin Chih-Cheng, Hsu Cheng-Hung, Wu Tieh-Kang, Huang Yu-Ting. (2012) Mechanical grinding effect on thermodynamics and inclusion efficiency of loratadine–cyclodextrin inclusion complex formation. Carbohydr. Polym. 87: 512-517. [SCI] (IF2020=9.381；R/C=1/58，CHEMISTRY, ORGANIC)
  35. Wu Tieh-Kang, Lin Shan-Yang*, Lin Hong-liang, Huang Yu-Ting. (2011) Simultaneous DSC-FTIR microspectroscopy used to screen and detect the co-crystal formation in real time. Bioorg. Med. Chem. Lett. 21: 3148-3151. [SCI] (IF2020=2.823；R/C=14/58，CHEMISTRY, ORGANIC)
  36. Lin Shan-Yang*, Cheng Wen-Ting, Wei Yen-Shan, Lin Hong-liang. (2011) DSC-FTIR microspectroscopy used to investigate the heat-induced intramolecular cyclic anhydride formation between Eudragit E and PVA copolymer. Polym. J. 43: 577–580. [SCI] (IF2020=3.080；R/C=42/90，POLYMER SCIENCE)
  37. Lin Hong-Liang, Lin Shyr-Yi, Lin Ying-Ku, Ho Hsiu-O, Lo Yo-Wen, Sheu Ming-Thau*. (2008) Release characteristics and in vitro–in vivo correlation of pulsatile pattern for a pulsatile drug delivery system activated by membrane rupture via osmotic pressure and swelling. Eur. J. Pharm. Biopharm. 70: 289–301. [SCI] (IF2020=5.571；R/C=19/352，PHARMACOLOGY & PHARMACY)
  38. Lin Hong-Liang, Ho Hsiu-O, Chen Chi-Chia, Yeh Ta-Shuong, Sheu Ming-Thau*. (2008) Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties. Int. J. Pharmaceut. 357: 206–212. [SCI] (IF2020=5.875；R/C=18/352，PHARMACOLOGY & PHARMACY)
🧾 研討會論文
※ 共計17篇，可上下捲動瀏覽
  1. 林志城、王元辰、莊路德、林宏糧、楊智強，「紅酒生產中減廢回收的多酚其保健機能與產品開發」，台灣食品科技學會第41次年會，嘉義：嘉義大學，民國100年12月2日－民國100年12月2日。
  2. Shan-Yang Lin, Wen-Ting Cheng, Hong-Liang Lin(林宏糧), Yu-Ting Huang, “Thermodynamics and Phase Transition of Metoclopramide HCl Monohydrate in the Dehydration and Recrystallization Processes,”15th International Congress on Thermal Analysis and Calorimetry (ICTAC15), Osaka, Osaka, Japan, 2012, 8, 20－2012, 8, 24.
  3. Wen-Ting Cheng, Hong-Liang Lin(林宏糧), Yu-Ting Huang, Shan-Yang Lin*, “Thermodynamics and Phase Transition of Metoclopramide HCL Monohydrate in the Dehydration and Recrystallization Processes,”15th International Congress on Thermal Analysis and Calorimetry, 大阪, 大阪, 日本, 2012, 8, 20－2012, 8, 24.
  4. Hong-Liang Lin(林宏糧), Po-Chun Hsu, Gang-Chun Zhang, Yu-Ting Huang, Shan-Yang Lin, “Grinding process-induced Cocrystal Formation Between Theophylline and Citric Acid,”2012年台灣藥學會, 中國醫藥大學, Taichung, Taiwan, 2012, 11, 25－2012, 11, 25.
  5. Hong-liang Lin(林宏糧),Ying-Ji Lin, Keng-long Chang, Jheng-kai Huang.「Development of Theophylline Sustained Release Dosage Forms」，2013中華民國生醫材料及藥物制放年會暨國科會成果發表，Kaohsiung：Taiwan，民國102年5月4日－民國102年5月5日。
  6. Hong-liang Lin(林宏糧), Gang-Chun Zhang, Yu-Ting Huang, Shan-Yang Lin, “Studies on Indomethacin-Saccharin Cocrystal Formation and Its Stability in Soft Gelatin Capsule ,”7th International Symposium on Acid-Base Catalysis, Japan, Tokyo, Japan, 2013, 5, 12－2013, 5, 15.
  7. Hong-Liang Lin(林宏糧), Po-Chun Hsu, Yu-Ting Huang, Shan-Yang Lin*, “Simultaneous DSC-FTIR Microspectroscopy Quickly Screen and Detect the Co-crystal Formation of Theophylline and Citric Acid,”Seventh International Conference on Advanced Vibrational Spectroscopy (ICAVS-7), 神戶, 神戶, 日本, 2013, 8, 25－2013, 8, 30.
  8. 林翰亞, 劉明憲, 林盈吉, 黃鉦凱, 林宏糧, “Formulation Design and Pharmacokinetic Study of Cyclobenzaprine HCl Extended Release Tablets in Healthy Volunteers,”2014年中華民國生醫材料及藥物制放研討會暨海峽兩岸生醫材料及藥物制放研討會 , 清華大學, 新竹, 台灣, 2014, 5, 2－2014, 5, 2.
  9. 黃鉦凱、劉明憲、林翰亞、林盈吉、黃懷翰、林宏糧，「海洋深層水礦質微粉化技術及錠劑產品開發」，2014年醫護與健康科技研討會，宜蘭：宜蘭，民國103年5月30日－民國103年5月30日。[佳作]
  10. Hong-Liang Lin(林宏糧).Formulation and Development of Dutasteride/Tamsulosin Pellets Dosage Form for Benign Prostatic Hyperplasia. 4th International Conference on“Medical, Medicine and Health Sciences”, 28-29 May , 2016 Osaka, Japan.
  11. Jia-Chi Fan, Guan-Wei Chen, Jiahorng Liaw, Shan-Yang Lin, Hong-Liang Lin(林宏糧), Wei-Hsien Hsieh. Sustained release formulation for citronella oil. 2016年台灣藥學會, 台北醫學大學, 2016/12/17, Taipei, Taiwan.
  12. Jia-Yin Liang, Hong-Liang Lin(林宏糧).Evaluation of the properties of Ibuprofen granules prepared by thermal adhesion granulation method. 2020中華民國生醫材料及藥物制放學會年會, 2020/08/18, Taipei, Taiwan.
  13. Fei-Shan Lin, Hong-Liang Lin(林宏糧).以Fenofibrate製備與開發自微乳化藥物傳遞系統研究. 2020中華民國生醫材料及藥物制放學會年會, 2020/08/18, Taipei, Taiwan.
  14. Chin-Hsuan Hung, Yu-Kai Liang and Hong-Liang Lin. Development of high-dose extended-release pellets of quetiapine with Eudragit RL and RS. 2021中華民國生醫材料及藥物制放學會年會 暨 2021科技部生科司工程醫學學門成果發表會。
  15. Yu-Ren Wang, Yu-Kai Liang and Hong-Liang Lin. Development of gastroretentive drug delivery system(GRDDS) of dipyridamole. 2022 中華民國生醫材料及藥物制放學會年會暨 科技部生科司工程醫學學門成果發表會。
  16. Yu-Kai Liang and Hong-Liang Lin*.Enhancement of therapeutic Effects on Pancreatic Cancer via Synergistic Triple-combination with Orally Administered Irinotecan, Rapamycin and Silymarin-loaded Self-microemulsifying Drug Delivery System. The 14th Cell and Gene Therapy Symposium and Antibody Engineering and Innovative Immunotherapy Technology Forum. 22-23 Sep, 2023, Shanghai, China.
  17. Yu-Kai Liang, Yu-Ren Wang, Hao-Yi Hsu and Hong-Liang Lin*. Non-covalent Decoration of Trispecific T-cell Engagers on PEGylated Micellar Nanocarriers for Prolonged Cancer Immunotherapy. The 29th Annual Meeting of Japanese Association of Cancer Immunology. 24-26 July, 2025, Nagoya, Japan.
📚 專書及專書論文
  1. Shan-Yang Lin, Shan-Yang Lin, Hong-Liang Lin(林宏糧), Chih-Cheng Lin, Cheng-Hung Hsu, Tieh-kang Wu, Yu-Ting Huang. Thermodynamic Study of Grinding-Induced Loratadine Inclusion Complex Formation Using Thermal Analysis and Curve-Fitted FTIR Determination, Thermodynamics – Physical Chemistry of Aqueous Systems, 978-953-307-3187, Juan Carlos Moreno-Pirajan, Intech, 2011, pp. 317-326.
  2. Lee T.H., Lin S.Y., Lin H.L.(林宏糧), Huang Y.T., Wu T.K., Lin C.C., Trehalose and mannitol improved thermal stability of salmon calcitonin in both aqueous solution and lyophilized solid form. Internat Proc. 4th Eur Conf Chem Life Sci. , 978-88-7587-631-9, Medimond, Bologna, Italy, 2011, pp.63-69.
🤝 專利/技術移轉
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  1. 中華民國專利證書 發明第 I 434930號
  2. 新穎性軟膠囊膠皮技術開發與安定性改善應用研究(NSC 101-2622-B-264-001-CC3)
  3. 控時釋放膜衣包覆技術
  4. 改善藥物溶解度固體分散技術
  5. 具難溶性藥品組合藥物制放技術平台產品(MOST 104–2622-B-264-001-CC2)
  6. Doxazosin XL 4mg Tablets產品處方與製程技術
  7. 微膠囊化技術開發高劑量紅藜錠劑產品
  8. 海洋深層水微粉化技術
  9. 控釋型肥料技術
🤝 產學合作計畫經費
※ 共計10案，可上下捲動瀏覽
  1. 鹽酸胺苯環庚烯緩釋錠劑處方開發研究計畫
  2. 治療轉移性結腸直腸癌 Oxaliplatin 50mg/10ml I.V.注射劑產品處方開發計畫
  3. PTS處方開發計畫
  4. IBUPROFEN高劑載處方研究開發計畫與推廣計畫
  5. Beatamethasone Dipropionate/ Clotrimazole/ Gentamicin Sulfate軟膏安定性改善計畫
  6. Chloramphenicol/ Dexamethasone 眼藥水安定性改善計畫
  7. 益生菌活菌顆粒劑產品開發計畫
  8. Sitagliptin處方設計與製程開發計畫
  9. 冬蟲夏草指標性成分分析與安定性評估
  10. 固定複方藥物西格列汀與二甲二胍延長釋放產品開發
🏆 獲獎紀錄
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  • 更新日期:2026-03-19